Novel cytotoxic macrolides and methods of use

Details Novel cytotoxic macrolides and methods of use Novel cytotoxic macrolides and methods of use

C - Chemistry, Metallurgy

07

H

C07H 19/01 (2006.01) A61K 31/70 (2006.01) C07D 309/10 (2006.01) C07D 309/30 (2006.01) C07D 493/18 (2006.01) C12P 17/18 (2006.01)

Patent

CA 2182878

A novel macrolide compound, lasonolide A, represented by chemical formula (1) has been isolated from a marine sponge. This compound, derivatives of the compound, and compositions comprising the compound or its derivatives, are useful as anti-tumor agents and as biochemical tools.

La présente invention concerne un nouveau composé macrolide, le lasonolide A, représenté par la formule chimique (1). Il a été isolé d'une éponge marine. Ce composé, ses dérivés et des compositions contenant ce composé ou ses dérivés peuvent être utilisés comme agents antitumoraux et comme auxiliaires biochimiques.

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