Novel d-homosteroids

Details Novel d-homosteroids Novel d-homosteroids

C - Chemistry, Metallurgy

07

J

260/4

C07J 63/00 (2006.01) C07J 21/00 (2006.01) C07J 41/00 (2006.01)

Patent

CA 1082686

ABSTRACT Compounds of the general formula Image (I) wherein the broken lines in the A-ring denote optional carbon-carbon bonds; R1 represents a hydrogen atom or a methyl group; R3 represents an oxo group or, when the A-ring is unsaturated, an oxo, (.alpha.-H, .beta.-OH) or (.alpha.-H, .beta.-O-acyl) group; R7 represents a hydrogen atom or a methyl group; R17a.beta. represents a hydrogen atom or a C1-10 alkyl, benzyl, cyclohexyl- methyl, acyl, tetrahydropyranyl or cycloalkenyl group; and R17a.alpha. represents a hydrogen atom or a lower alkyl, ethynyl, vinyl or propadienyl group, which are useful for the manufacture of pharmaceutical pre- parations with hormonal activity, and method for the pre- paration thereof.

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