Novel delta dicarbonyl compounds and methods for using same

Details Novel delta dicarbonyl compounds and methods for using same Novel delta dicarbonyl compounds and methods for using same

C - Chemistry, Metallurgy

07

C

C07C 233/36 (2006.01) A61K 31/121 (2006.01) A61K 31/16 (2006.01) C07C 69/52 (2006.01) C07C 69/618 (2006.01) C07C 219/00 (2006.01) C07C 233/05 (2006.01) C07C 233/18 (2006.01) C07C 233/22 (2006.01) C07C 233/31 (2006.01) C07C 235/08 (2006.01) C07C 327/22 (2006.01) C07C 327/28 (2006.01)

Patent

CA 2363758

Amidomethyl esters, carbonylmercaptomethyl esters, keto-containing esters, amidomethyl thioesters, amidomethyl amides, and methylene dithioesters are disclosed. The novel compounds have two carbonyl groups connected by a linking moiety having an oxygen, sulfur or nitrogen attached to a methylene group, to which is further attached a sulfur, nitrogen or CH2 group. Methods of treating illnesses and conditions, such as cancer, hemological disorders, inherited metabolic disorders and others, using these compounds are also disclosed.

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