Novel derivatives of...

A - Human Necessities – 61 – P

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A61P 25/28 (2006.01) A61K 31/55 (2006.01) A61P 3/10 (2006.01) A61P 9/10 (2006.01) A61P 25/00 (2006.01) A61P 25/08 (2006.01) A61P 25/14 (2006.01) A61P 25/16 (2006.01) C07D 491/10 (2006.01)

Patent

CA 2539961

The invention relates to novel derivatives of 4a,5,9,10,11,12-hexahydro- benzofuro[3a,3,2] [2]benzazepine of general formulae 1a, 1b and 1c. Compounds 1a, 1b and 1c can be produced in an efficient manner on an industrial scale with the desired optical purity and are suitable for the production of medicaments for the treatment of a diverse range of symptoms, particularly diseases of the central nervous system (CNS), on account of the pharmacological effect thereof.

La présente invention concerne de nouveaux dérivés de 4a,5,9,10,11,12-hexahydro-benzofuro[3a,3,2] [2]benzazépine de formules générales Ia, Ib et Ic. Les composés de formules Ia, Ib et Ic peuvent non seulement être préparés à l'échelle industrielle de façon efficace, avec une pureté optique souhaitée, mais conviennent aussi, en raison de leur action pharmacologique, à la préparation de produits pharmaceutiques destinés au traitement de différentes formes de maladies, en particulier de troubles du système nerveux central (SNC).

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