Novel derivatives of androstane and androstene with ascorbic...

C - Chemistry – Metallurgy – 07 – J

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C07J 17/00 (2006.01) A61K 31/58 (2006.01) A61K 31/585 (2006.01) A61P 3/04 (2006.01) A61P 7/12 (2006.01) C07J 1/00 (2006.01) C07J 19/00 (2006.01)

Patent

CA 2488618

The present invention provides novel derivatives comprising compounds in the androstane and androstene series, coupled with ascorbic acid, including salts thereof, and represented by one or more of the general formulae (I), (II), (III): wherein R1, R2, R3, R4, R5, R6 may individually be chosen from hydrogen, OH, carbonyl, and an ascorbyl moiety; and R7 may be hydrogen or any halogen.

La présente invention concerne de nouveaux dérivés comprenant des composés dans les séries d'androstane et d'androstène, couplés avec un acide ascorbique, comprenant leurs sels, et représentés par une ou plusieurs des formule(s) générale(s) (I),(II), (III):, dans laquelle (dans lesquelles) R¿1?, R¿2?, R¿3?, R¿4?, R¿5?, R¿6? peuvent être sélectionnés individuellement dans le groupe hydrogène, OH, carbonyle, et un fragment d'ascorbyle; et R¿7? peut désigner hydrogène ou tout halogène.

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