C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 241/44 (2006.01) A61K 31/495 (2006.01)
Patent
CA 2214572
The present invention relates to novel derivatives of ethyl-1 dihydro-1,2 oxo-2 methylamino-3 quinoxaline having general formula (I), wherein R1 is hydrogen or methyl group, and the salt thereof with pharmaceutically acceptable acids. It also relates to their utilization as drugs useful particularly in the treatment of diseases such as chronic obstructive bronchopneumopathies, particularly asthma, respiratory insufficency, emphysema. Finally, it relates to pharmaceutically compositions containing them.
La présente invention concerne de nouveaux dérivés de l'éthyl-1 dihydro-1,2 oxo-2 méthylamino-3 quinoxaline de formule générale (I), dans laquelle R1 représente l'hydrogène ou le groupe méthyle, et leurs sels avec des acides pharmaceutiquement acceptables. Elle concerne également leur utilisation à titre de médicaments utiles en particulier dans le traitement des maladies telles que les bronchopneumopathies obstructives chroniques notamment l'asthme, l'insuffisance respiratoire, l'emphysème. Elle concerne enfin les compositions pharmaceutiques les comprenant.
Autin Jean-Marie
Patoiseau Jean-Francois
Tarayre Jean-Pierre
Pierre Fabre Medicament
Swabey Ogilvy Renault
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