Novel derivatives of isoquinoline, process for their...

C - Chemistry – Metallurgy – 07 – D

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C07D 217/14 (2006.01) A61K 31/472 (2006.01) C07D 217/16 (2006.01)

Patent

CA 2462939

The invention relatests compound of formula (I): (see formula 1) wherein: ~ n is 1, 2 or 3, ~ A represents a group (see formula II), (see formula III) or group (see formula IV) ~X represents N or NR1, ~ R2 represents an alkoxy, cycloalkyloxy or cycloalkylalkyloxy group and representation ~ meaning that the bond is single or double, with the proviso that the valency of the atoms is respected. The present invention also relates to their process of their preparation and to pharmaceutical compositions containing them.

La présente invention concerne des composés de formule (I): (voir formule I) dans laquelle : ~ n vaut 1, 2 ou 3, ~ A représente un groupement (voir formule II), (voir formule III) ou un groupement (voir formule IV) ~ X représente N ou NR1 ~ R2 représente un groupement alkoxy, cycloalkyloxy ou cycloalkylalkyloxy et la représentation ~ signifie que la liaison est simple ou double étant entendu que la valence des atomes est respectée, la présente invention concerne également leur procédé de préparation, leur utilisation et les compositions pharmaceutiques qui les contiennent.

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