C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/68 (2006.01) C12N 7/04 (2006.01) C12N 15/86 (2006.01) C12Q 1/70 (2006.01)
Patent
CA 2370957
The invention provides replication incompetent viral particles that are engineered to contain one or more primer binding sites that are homologous to similar sites found in one or more target wild type viral genomes. Accordingly, the invention also provides methods of using the replication incompetent viral particles as controls for the detection and/or quantification of wild type viruses.
L'invention concerne des particules virales incapables de se répliquer et que l'on a modifiées génétiquement de manière qu'elles contiennent au moins un site de liaison d'amorce qui soit homologue aux sites trouvés dans au moins un génome viral de type sauvage. En conséquence, l'invention concerne des procédés d'utilisation de ces particules virales incapables de se répliquer, en tant que témoins dans la détection et/ou quantification de virus de type sauvage.
Shih James W.
Wang Richard Yuan-Hu
Smart & Biggar
The Government Of The United States Of America
LandOfFree
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