Novel dicarboxylic acid derivatives as s1p1 receptor agonists

Details Novel dicarboxylic acid derivatives as s1p1 receptor agonists Novel dicarboxylic acid derivatives as s1p1 receptor agonists

C - Chemistry, Metallurgy

07

D

C07D 271/06 (2006.01) A61K 31/4245 (2006.01) A61P 29/00 (2006.01) A61P 37/06 (2006.01) C07D 413/10 (2006.01) C07D 413/14 (2006.01)

Patent

CA 2693126

The present invention relates to new compounds of formula (I) possessing agonistic activity at sphingosine-1 -phosphate (S1 P) receptors, their process of preparation and their use as immunosuppressive agents. The invention is also directed to pharmaceutical compositions containing these compounds and use of these compounds for treatment/prevention of immune medi-ated diseases and conditions or inflammatory diseases and conditions.

La présente invention concerne de nouveaux composés représentés par la formule générale (I) exerçant une activité agoniste contre les récepteurs de la sphingosine-1-phosphate (S1P), leur procédé de préparation et leur utilisation comme agents immunosuppresseurs. L'invention concerne également des compositions pharmaceutiques contenant ces composés et l'utilisation de ces composés pour le traitement/la prévention de maladies et de troubles induits par le système immunitaire ou de maladies et de troubles inflammatoires.

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