C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 59/64 (2006.01) A61K 31/192 (2006.01) A61P 3/10 (2006.01)
Patent
CA 2397076
Novel diphenylethylene compounds that are administered orally to decrease circulating concentrations of glucose are provided. The effect on insulin resistant rats is also shown. The effects on lipid and leptin concentrations are also shown. The compounds are orally effective anti-diabetic agents that may normalize glucose and lipid metabolism in subjects with diabetes.
L'invention concerne de nouveaux composés de diphényléthylène administrés oralement de façon à réduire les concentrations de glucose qui circulent. L'invention concerne également l'effet desdits composés sur les rats résistants à l'insuline, ainsi que leur effet sur les concentrations lipidiques et leptiniques. Ces composés sont des agents antidiabétiques oralement efficaces pouvant normaliser le métabolisme du glucose et des lipides chez des sujets souffrant de diabètes.
Dey Debendranath
Medicherla Satyanarayana
Nag Bishwajit
Neogi Partha
Calyx Therapeutics Inc.
Gowan Intellectual Property
Theracos Inc.
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