Novel dna sequences which encode ancrod-like polypeptides...

C - Chemistry – Metallurgy – 12 – N

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530/13, 167/327,

C12N 15/70 (2006.01) A61K 35/58 (2006.01) A61L 27/00 (2006.01) A61L 27/22 (2006.01) A61L 29/04 (2006.01) C12N 1/00 (2006.01) C12N 9/48 (2006.01) C12N 9/64 (2006.01) C12N 15/57 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2015127

ABSTRACT The present invention relates to novel DNA sequences which encode polypeptides displaying the activity of ancrod and to recombinant DNA molecules which comprise them. The invention also relates to hosts transformed with these DNA molecules as well as to the recombinant polypeptides expressed by them. This invention further relates to pharmaceutically effective compositions and methods which employ these recombinant polypeptides.

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