C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 471/04 (2006.01) A61K 31/422 (2006.01) A61K 31/437 (2006.01) A61K 31/4375 (2006.01) A61K 31/4439 (2006.01) A61K 31/4709 (2006.01) A61P 9/12 (2006.01) C07D 413/14 (2006.01) C07D 417/14 (2006.01)
Patent
CA 2644578
The present invention relates to new compounds of the formula [Chemical formula should be inserted here. Please see paper copy] wherein R1, R2, R3, and R31 are as specified herein. The invention also relates to a method for preparation thereof, as well as combinations of the new compounds with previously known agents. The invention also relates to the use of the above-mentioned compounds and combinations for the preparation of a medicament for treating hypertension of different kinds, alleviating organ damage of different kinds, treating or preventing diabetic nephropathy, treating endothelin and angiotensin mediated disorders, and treating prostate cancer.
La présente invention concerne de nouveaux composés de formule [Chemical formula should be inserted here. Please see paper copy] dans laquelle R1, R2, R3 et R31 sont tels que spécifiés dans le présent document. L'invention concerne également un procédé de préparation de ces composés, ainsi que des combinaisons des nouveaux composés et des agents déjà connus. L'invention concerne également l'utilisation des composés et combinaisons susmentionnés pour la fabrication d'un médicament pour traiter l'hypertension de différents types, pour soulager les endommagements d'organe de différents types, pour traiter ou prévenir la néphropathie diabétique, pour traiter les troubles induits par l'endothéline et l'angiotensine, et pour traiter le cancer de la prostate.
Gupta Ramesh Chandra
Jagtap Vikrant Vijaykumar
Mandhare Appaji Baburao
Perkins Tim
Westerlund Christer
Bcf Llp
Torrent Pharmaceuticals Ltd
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