C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 211/66 (2006.01) A61K 31/44 (2006.01) A61K 31/443 (2006.01) A61K 31/4433 (2006.01) A61K 31/4439 (2006.01) A61K 31/444 (2006.01) A61K 31/445 (2006.01) C07D 211/58 (2006.01) C07D 211/62 (2006.01) C07D 295/14 (2006.01) C07D 401/04 (2006.01) C07D 401/12 (2006.01) C07D 405/12 (2006.01) C07D 409/12 (2006.01) C07D 413/12 (2006.01)
Patent
CA 2641817
The present invention relates to novel dual NK2/NK3-antagonists of formula (I) wherein the meaning of X and R1 to R5 is defined in the claims and in the description and also to pharmaceutical compositions comprising these compounds. Furthermore, the invention relates to processes for the preparation of the novel dual NK2/NK3-antagonists and to their uses.
La présente invention concerne des nouveaux antagonistes doubles de NK2/NK3 de formule (I) dans laquelle la signification de X et celle de R1 à R5 est telle que définie dans les revendications et dans la description. L'invention concerne également des compositions pharmaceutiques comprenant ces composés. En outre, l'invention concerne des procédés de préparation des nouveaux antagonistes doubles de NK2/NK3 et leurs utilisations.
Adolfs Martinus
Attali Amos
Benson Werner
Bruckner Reinhard
Firnges Michael
Mccarthy Tetrault Llp
Solvay Pharmaceuticals Gmbh
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