Novel ecdysone receptor-based inducible gene expression system

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/63 (2006.01) A01H 5/00 (2006.01) C07K 14/705 (2006.01) C07K 14/72 (2006.01) C12N 15/12 (2006.01) C12N 15/62 (2006.01) C12N 15/85 (2006.01) C12Q 1/68 (2006.01) G01N 33/68 (2006.01) A61K 38/00 (2006.01) A61K 48/00 (2006.01)

Patent

CA 2404253

This invention relates to the field of biotechnology or genetic engineering. Specifically, this invention relates to the field of gene expression. More specifically, this invention relates to a novel inducible gene expression system and methods of modulating gene expression in a host cell for applications such as gene therapy, large scale production of proteins and antibodies, cell-based high throughput screening assays, functional genomics and regulation of traits in transgenic plants and animals.

L'invention concerne le domaine de la biotechnologie ou du génie génétique. En particulier, l'invention concerne l'expression génétique, et plus particulièrement, un système d'expression génétique inductible et des méthodes permettant de moduler l'expression dans une cellule hôte pour des applications, telles que la thérapie génique, la production à grande échelle de protéines et d'anticorps, des tests de criblage cellulaire à haut rendement, la génomique fonctionnelle et la régulation de caractéristiques dans des plantes et des animaux transgéniques.

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