C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/12 (2006.01) A01K 67/027 (2006.01) C07K 14/705 (2006.01) C07K 14/72 (2006.01) C12N 1/19 (2006.01) C12N 1/21 (2006.01) C12N 5/10 (2006.01) C12N 15/63 (2006.01)
Patent
CA 2441444
This invention relates to the field of biotechnology or genetic engineering. Specifically, this invention relates to the field of gene expression. More specifically, this invention relates to a novel ecdysone receptor/invertebrate retinoid X receptor-based inducible gene expression system and methods of modulating gene expression in a host cell for applications such as gene therapy, large-scale production of proteins and antibodies, cell-based high throughput screening assays, functional genomics and regulation of traits in transgenic organisms.
Cette invention concerne la biotechnologie ou le génie génétique. Plus spécifiquement, cette invention concerne l'expression génétique. Plus spécifiquement encore, cette invention concerne un nouveau système d'expression génétique inductible basé sur le récepteur d'ecdysone/récepteur de rétinoïde X invertébré, des procédés de modulation de l'expression génétique dans une cellule hôte pour des applications telles que thérapie génique, production à grande échelle de protéines et d'anticorps, essais de criblage à grand rendement basés sur des cellules, génomique fonctionnelle et régulation de certains caractères dans des organismes transgéniques.
Kapitskaya Marianna Zinovjevna
Palli Subba Reddy
Gowling Lafleur Henderson Llp
Intrexon Corporation
Rheogene Holdings Inc.
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