Novel ectoparasite saliva proteins and apparatus to collect...

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/12 (2006.01) A61K 39/35 (2006.01) A61K 49/00 (2006.01) C07K 14/435 (2006.01) C07K 16/18 (2006.01) C12N 7/01 (2006.01) G01N 33/564 (2006.01) A61K 38/00 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2250835

The present invention is directed to a novel product and method for isolating ectoparasite saliva proteins, and a novel product and method for detecting and/or treating allergic dermatitis in an animal. The present invention also relates to ectoparasite saliva proteins, nucleic acid molecules having sequences that encode such proteins, and antibodies raised against such proteins. The present invention also includes methods to obtain such proteins and to use such proteins to identify animals susceptible to or having allergic dermatitis. The present invention also includes therapeutic compositions comprising such proteins and their use to treat animals susceptible to or having allergic dermatitis.

La présente invention concerne un nouveau produit et un nouveau procédé pour isoler des protéines de salive d'ectoparasite, ainsi qu'un nouveau produit et un nouveau procédé pour détecter et/ou traiter l'eczéma allergique chez un animal. L'invention concerne également des protéines de salive d'ectoparasite, des molécules d'acide nucléique présentant des séquences codant pour ces protéines, et des anticorps dirigés contre ces dernières. Elle concerne d'autre part des procédés pour obtenir de telles protéines et pour les utiliser en vue d'identifier des animaux prédisposés à l'eczéma allergique ou en souffrant. La présente invention a trait par ailleurs à des compositions thérapeutiques comprenant ces protéines et à leur utilisation pour traiter des animaux prédisposés à l'eczéma allergique ou en souffrant.

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