Novel eimeria antibodies and antigens and methods of using...

Details Novel eimeria antibodies and antigens and methods of using... Novel eimeria antibodies and antigens and methods of using...

C - Chemistry, Metallurgy

07

K

C07K 16/20 (2006.01) A61K 39/395 (2006.01) C07K 14/455 (2006.01) G01N 33/569 (2006.01) G01N 33/577 (2006.01)

Patent

CA 2167533

Novel stage-specific and intracellular protective Eimeria antigens are disclosed. The antigens are identifiable using antibody preparations produced locally, at the site of parasitic infection. The antibodies and antigens are useful as diagnostic reagents to detect coccidiosis as well as to determine the state of immunity of a particular avian subject. The antibodies and antigens are also useful in vaccine compositions to provide protection against Eimeria infection.

Sont décrits de nouveaux antigènes d'Eimeria protecteurs intracellulaires et spécifiques du stade. Ces antigènes sont identifiables à l'aide de préparations d'anticorps produites localement, au niveau du site de l'infection parasitaire. Les anticorps et les antigènes sont utiles comme réactifs diagnostiques pour détecter la coccidiose ainsi que pour déterminer l'état immunitaire d'un sujet aviaire donné. Ces anticorps et ces antigènes sont également utiles dans des compositions de vaccin assurant une protection contre l'infection par Eimeria.

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