Novel enhancer sequences for late t cell expressed genes

Details Novel enhancer sequences for late t cell expressed genes Novel enhancer sequences for late t cell expressed genes

C - Chemistry, Metallurgy

12

N

C12N 15/11 (2006.01) C07H 21/00 (2006.01) C07K 14/47 (2006.01) C07K 14/52 (2006.01) C12N 15/67 (2006.01) C12N 15/85 (2006.01) C12Q 1/02 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2224723

Novel transcription enhancer elements - particularly R(A) and R(C) - have been identified and isolated from the native RANTES genomic DNA. Means are provided for using these elements to enhance gene expression and to identify modulators of native RANTES protein expression.

On a identifié et isolé de nouveaux éléments amplificateurs de transcription - en particulier R(A) et R(C) - à partir de l'ADN génomique de RANTES natif. L'invention concerne des moyens permettant d'utiliser ces éléments pour amplifier l'expression des gènes et identifier des modulateurs de l'expression de la protéine de RANTES natif.

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