Novel epoxide-containing compounds

C - Chemistry – Metallurgy – 07 – K

Patent

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C07K 5/06 (2006.01) A61K 31/33 (2006.01) A61K 38/05 (2006.01) C07D 303/36 (2006.01) C07D 303/46 (2006.01) C07D 405/06 (2006.01) C07D 473/06 (2006.01) C07D 473/10 (2006.01) C07D 487/04 (2006.01) A61K 7/06 (1995.01)

Patent

CA 2145192

Compounds comprise epoxide-substituted alkyl side chain (R) bonded to a core moiety, comprising Core moiety (I), wher- ein n is an integer from about 4 to about 16 and j is an integer from about 0 to about 12, including resolved enantiomers and/or diastereomers, salts, solvates, hydrates and mixtures thereof. Preferably, n is an integer from about 4 to about 12, more preferably from about 4 to about 10.j is preferably an integer from about 0 to about 3. The alkyl groups may also be substituted by a hydrox- yl, halo or dimethylamino group and/or interrupted by an oxygen atom, H or alkyl (1-4C).

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