Novel erythromycin derivatives, method for preparing same,...

C - Chemistry – Metallurgy – 07 – H

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C07H 17/00 (2006.01) A61K 31/70 (2006.01) C07H 17/08 (2006.01)

Patent

CA 2247175

Compounds of formula (I), wherein X is a CH2 or SO2 radical or an oxygen atom, Y is a (CH2)m-(CH=CH)n(CH2)o radical, where m + n + o </=8,n = 0 or 1, Ar is an aryl radical and W is hydrogen atom or a carbamate function residue are disclosed. The compounds of formula (I) have valuable antibiotic properties.

L'invention a pour objet les composés de formule (I) dans lesquels: X représente un radical CH2 ou SO2 ou un atome d'oxygène, Y représente un radical (CH2)n,-(CH=CH)n(CH2)o, avec m + n + o <= 8, n = 0 ou 1, Ar représente un radical aryle, W représente un atome d'hydrogène, ou le reste d'une fonction carbamate. Les composés de formule (I) présentent d'intéressantes propriétés antibiotiques.

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