Novel erythromycin derivatives, method for preparing them...

Details Novel erythromycin derivatives, method for preparing them... Novel erythromycin derivatives, method for preparing them...

C - Chemistry, Metallurgy

07

H

C07H 17/08 (2006.01) A61K 31/70 (2006.01)

Patent

CA 2273985

The invention concerns compounds of formula (I) in which R represents an alkyl radical optionally substituted or (CH2)nAr, n representing a whole number ranging from 0 to 6 and Ar representing an aryl or heteroaryl radical optionally substituted, and Z represents a hydrogen atom or the radical of a carboxylic acid. The compounds of formula (I) have very interesting antibiotic properties.

L'invention a pour objet les composés de formule (I) dans lesquels R représente un radical alkyle éventuellement substitué ou (CH2)n Ar, n représentant un nombre entier allant de 0 à 6 et Ar représentant un radical aryle ou hétéroaryle éventuellement substitué, et Z représente un atome d'hydrogène ou le reste d'un acide carboxylique. Les composés de formule (I) présentent d'intéressantes propriétés antibiotiques.

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