C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/12 (2006.01) C07H 21/04 (2006.01) C07K 14/00 (2006.01) C07K 14/47 (2006.01) C07K 14/705 (2006.01) C12N 5/10 (2006.01) C12N 15/63 (2006.01) C12N 15/66 (2006.01) C12N 15/85 (2006.01) C12N 15/86 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2339406
The present ivention provides a novel potassium channel subunit (ESK) and polynucleotides which identify and encode ESK. The invention also provides expression vectors and host cells comprising nucleic acid sequence encoding ESK. The invention also provides antibodies of ESK and methods of diagnosing and treating diseases associated with expression of ESK, and screening assays employing the polypeptide, nucleotide, and antibody compositions.
La présente invention concerne une nouvelle sous-unité (ESK) du canal potassium et des polynucléotides identifiant et codant ESK. L'invention concerne également des vecteurs d'expression et des cellules hôtes comprenant une séquence d'acide nucléique codant ESK. L'invention concerne en outre des anticorps d'ESK et des méthodes de diagnostic et de traitement d'affections liées à l'expression d'ESK, ainsi que des dosages biologiques de criblage faisant appel aux compositions de polypeptides, de nucléotides et d'anticorps.
Forsayeth John R.
Zhao Byron B.
Elan Pharmaceuticals Inc.
Gowling Lafleur Henderson Llp
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