Novel extracellular serine protease

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 1/21 (2006.01) C12N 5/10 (2006.01) C12N 9/48 (2006.01) C12N 9/50 (2006.01) C12N 9/64 (2006.01) C12N 15/55 (2006.01) C12N 15/63 (2006.01)

Patent

CA 2301902

The present invention provides a DNA encoding a TADG-14 protein selected from the group consisting of: (a) isolated DNA which encodes a TADG-14.protein; (b) isolated DNA which hybridizes to isolated DNA of (a) above and which encodes a TADG-14 protein; and (c) isolated DNA differing from the isolated DNAs of (a) and (b) above in codon sequence due to the degeneracy of the genetic code, and which encodes a TADG-14 protein. Also provided is a vector capable of expressing the DNA of the present invention adapted for expression in a recombinant cell and regulatory elements necessary for expression of the DNA in the cell.

L'invention concerne un ADN codant une protéine de TADG-14, choisi dans le groupe comprenant: (a) un ADN isolé qui code un protéine de TADG-14; (b) un ADN isolé qui s'hybride avec l'ADN isolé de (a) et qui code une protéine de TADG-14; et (c) un ADN isolé différent des ADN isolés de (a) et (b) dans une séquence de codon, en raison de la dégénérescence du code génétique, et qui code une protéine de TADG-14. L'invention porte aussi sur un vecteur capable d'exprimer l'ADN de l'invention, conçu pour l'expression dans une cellule recombinée, et sur les éléments nécessaires à l'expression de l'ADN dans la cellule.

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