C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/12 (2006.01) A61K 31/70 (2006.01) A61K 38/17 (2006.01) C07K 14/705 (2006.01) C07K 14/735 (2006.01) C07K 16/18 (2006.01) C07K 16/28 (2006.01) C12N 5/10 (2006.01) C12N 7/01 (2006.01) C12N 15/86 (2006.01) C12Q 1/68 (2006.01) G01N 33/50 (2006.01) G01N 33/53 (2006.01) G01N 33/566 (2006.01) G01N 33/68 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2273855
The present invention relates to feline Fc epsilon receptor alpha chain nucleic acid molecules, proteins encoded by such nucleic acid molecules, antibodies raised against such proteins, and inhibitors of such proteins. The present invention also includes methods to detect IgE using such proteins and antibodies. Also included in the present invention are therapeutic compositions comprising such proteins, nucleic acid molecules, antibodies and/or inhibitory compounds as well as the use of such therapeutic compositions to mediate Fc epsilon receptor-mediated biological responses.
Cette invention a trait à de nouvelles molécules d'acide nucléique à chaîne alpha du récepteur epsilon du Fc félin, à des protéines codées par cet acide nucléique et à des anticorps allant à l'encontre de ces protéines ainsi qu'à des inhibiteurs desdites protéines. Elle porte également sur des techniques de détection d'immunoglobuline E (IgE) faisant intervenir ces protéines et ces anticorps. Elle concerne, de surcroît, des compositions thérapeutiques renfermant ces protéines, des molécules d'acide nucléique, des anticorps et/ou des composés inhibiteurs, ainsi que l'usage qui est fait desdites compositions dans le but d'agir sur des réponses biologiques induites par le récepteur epsilon du Fc.
Frank Glenn Robert
Porter James P.
Rushlow Keith E.
Wassom Donald L.
Weber Eric R.
Borden Ladner Gervais Llp
Heska Corporation
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