Novel fenofibrate formulations and related methods of treatment

A - Human Necessities – 61 – K

Patent

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A61K 9/00 (2006.01)

Patent

CA 2573316

The invention provides novel omega-3 ester-based oil solutions of fenofibrate. These solutions are substantially free of any food effect, effective in small volumes, and readily bioavailable. Notably, because the solutions of the invention contain an omega-3 ester-based oil as the major ingredient, the y not only provide an antihyperlipidemic effect due to the fenofibrate active ingredient, they also provide recommended daily dosages of omega-3 oils (i.e., approximately 1 gram of omega-3 oil per day), or a portion thereof.

L'invention concerne de nouvelles solutions d'huiles à base d'esters oméga 3 de fénofibrate. Lesdites solutions sont sensiblement dépourvues d'effet nourrissant, efficaces à faibles volumes et facilement biodisponibles. Notamment, étant donné que les solutions de l'invention contiennent une huile à base d'esters oméga 3 en tant qu'ingrédient principal, elles assurent non seulement un effet antihyperlipidémique dû à l'ingrédient actif de fénofibrate, mais elle assurent également les doses quotidiennes recommandées d'huiles oméga 3 (c'est-à-dire, approximativement 1 gramme d'huile oméga 3 par jour), ou une partie de ces dernières.

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