Novel fibroblast growth factors and methods of use thereof

A - Human Necessities – 61 – K

Patent

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A61K 38/18 (2006.01) A61P 29/00 (2006.01)

Patent

CA 2525107

The present invention relates to compositions and methods of treatment of various conditions, including but are not limited to, stroke, wound healing, and joint diseases (e.g., osteoarthritis and rheumatoid arthritis). More particularly, the present invention relates to compositions comprising a member of the fibroblast growth factor family, FGF-CX (also known as CG53135- 05 or FGF-20), its related polypeptides, nucleic acids encoding such polypeptides, and their uses for treating a condition, such as but is not limited to, stroke, wound healing, and joint diseases (e.g., osteoarthritis and rheumatoid arthritis).

La présente invention concerne des compositions et des procédés pour traiter diverses pathologies, notamment un accident vasculaire cérébral, une cicatrisation et des maladies articulaires (par ex. l'ostéoarthrose et la polyarthrite rhumatoïde). Cette invention concerne plus particulièrement des compositions comprenant un membre de la famille des facteurs de croissance des fibroblastes, FGF-CX (également connu sous la dénomination CG53135-05 ou FGF-20), ses polypeptides associés, des acides nucléiques codant de tels polypeptides, ainsi que leurs utilisations pour traiter une pathologie, notamment un accident vasculaire cérébral, une cicatrisation et des maladies articulaires (par ex. l'ostéoarthrose et la polyarthrite rhumatoïde).

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