Novel fibronectin-binding protein

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/11 (2006.01) A61K 39/09 (2006.01) C07K 14/315 (2006.01) C07K 16/12 (2006.01) C12N 5/10 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2355831

The present invention is concerned with a novel fibronectin-binding protein of Streptococcus equi, to a DNA fragment encoding this protein, to host cells and vectors containing said DNA fragment and to methods to produce said protein based on recombinant DNA technology. The invention is also related to use of said protein in the preparation of a vaccine, to a vaccine containing said protein, to antibodies specific for said protein and to polyvalent antisera containing such antibodies.

L'invention concerne une nouvelle protéine de Streptococcus equi fixant la fibronectine, un fragment d'ADN codant cette protéine, des cellules et des vecteurs hôtes contenant ledit fragment d'ADN, ainsi que des méthodes de production de ladite protéine par génie génétique. L'invention concerne également l'utilisation de ladite protéine dans la préparation d'un vaccin, un vaccin renfermant ladite protéine, des anticorps spécifiques à ladite protéine, ainsi que les antisérums polyvalents renfermant de tels anticorps.

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