C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/62 (2006.01) A01K 67/027 (2006.01) A61K 38/39 (2006.01) A61K 39/395 (2006.01) A61K 48/00 (2006.01) C07K 14/78 (2006.01) C07K 16/18 (2006.01) C07K 19/00 (2006.01) C12N 1/21 (2006.01) C12N 5/10 (2006.01) C12N 15/12 (2006.01) C12N 15/63 (2006.01) C12P 21/02 (2006.01) C12Q 1/02 (2006.01) C12Q 1/68 (2006.01) G01N 33/48 (2006.01) G01N 33/50 (2006.01) G01N 33/53 (2006.01) G01N 33/566 (2006.01)
Patent
CA 2511853
The present invention discloses open reading frames (ORFs) in human genome encoding for novel fibulin-like polypeptides, and reagents related thereto including variants, mutants and fragments of said polypeptides, as well as ligands and antagonists directed against them. The invention provides methods for identifying and making these molecules, for preparing pharmaceutical compositions containing them, and for using them in the diagnosis, prevention and treatment of diseases.
Cette invention se rapporte à des cadres de lecture ouverts (ORF) du génome humain codant de nouveaux polypeptides de type fibuline, et à des réactifs relatifs à ceux-ci, y compris des variants, des mutants et des fragments de ces polypeptides, ainsi que des ligands et des antagonistes dirigés contre eux. Cette invention concerne des procédés pour identifier et fabriquer ces molécules, pour préparer des compositions pharmaceutiques contenant ces molécules et pour utiliser ces compositions et molécules dans le diagnostic, la prévention et le traitement de maladies.
Bienkowska Jadwiga
Mcallister Gregg
Applied Research Systems Ars Holding N.v.
Borden Ladner Gervais Llp
Laboratoires Serono S.a.
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