Novel flavivirus antigens

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/40 (2006.01) A61K 38/16 (2006.01) A61K 39/12 (2006.01) A61K 48/00 (2006.01) A61P 31/14 (2006.01) C07K 14/18 (2006.01) C07K 16/10 (2006.01) C12N 7/01 (2006.01) C12N 15/86 (2006.01) C12P 21/08 (2006.01)

Patent

CA 2481479

The invention provides polynucleotides and polypeptides encoded therefrom having advantageous properties, including an ability to induce an immune response to flaviviruses. The polypeptides and polynucleotides of the invention are useful in methods of inducing immune response against flaviviruses, including dengue viruses. Compositions and methods for utilizing polynucleotides and polypeptides of the invention are also provided.

La présente invention concerne des polynucléotides et des polypeptides codés à partir de ces derniers présentant des propriétés avantageuses, notamment une capacité à induire une réponse immunitaire aux flavivirus. Lesdits polypeptides et polynucléotides selon l'invention sont utiles dans des méthodes d'induction de réponse immunitaire dirigée contre des flavivirus, notamment contre des virus de la dengue. L'invention concerne également des compositions et des méthodes d'utilisation desdits polynucléotides et polypeptides.

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