Novel forms of bendamustine free base

Details Novel forms of bendamustine free base Novel forms of bendamustine free base

A - Human Necessities

61

K

A61K 31/4184 (2006.01) C07D 235/16 (2006.01)

Patent

CA 2749101

Novel polymorphic forms of bendamustine free base are described, including amorphous bendamustine free base, six anhydrous crystalline forms, four hydrate forms, and five solvate forms, with methods of their preparation and use also being described.

L'invention porte sur de nouvelles formes polymères de base libre de bendamustine, comprenant une base libre de bendamustine amorphe, six formes cristallines anhydres, quatre formes d'hydrates et cinq formes de solvates, avec en outre la description de procédés pour leur préparation et leur utilisation.

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