Novel forms of pravastatin sodium

C - Chemistry – Metallurgy – 07 – C

Patent

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C07C 69/33 (2006.01) A61K 31/22 (2006.01) A61P 3/00 (2006.01) A61P 9/10 (2006.01)

Patent

CA 2551203

New polymorphic forms of pravastatin sodium are provided. Each of the new forms is selectively obtained by crystallization from different solvent systems, each solvent system having a protic component, and by controlling the rate of crystallization through temperature. The new polymorphic foams are suitable for use as active substances of pharmaceutical dosage forms for reduction of serum cholesterol levels in the bloodstream.

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