Novel formulations for treatment of migraine

Details Novel formulations for treatment of migraine Novel formulations for treatment of migraine

A - Human Necessities

61

K

A61K 31/404 (2006.01) A61K 9/00 (2006.01) A61K 31/403 (2006.01) A61K 31/4178 (2006.01) A61K 31/4196 (2006.01) A61K 31/422 (2006.01) A61K 31/454 (2006.01) A61K 31/46 (2006.01) A61P 25/06 (2006.01)

Patent

CA 2722743

Systems and methods are described for treating un-met medical needs in migraine and related conditions such as cluster headache. Included are treatments that are both rapid onset and long acting, which include sustained release formulations, and combination products. Also included are treatments for multiple symptoms of migraine, especially headache and nausea and vomiting. Systems that are self contained, portable, prefilled, and simple to self administer at the onset of a migraine attack are disclosed, and preferably include a needle-free injector and a high viscosity formulation, to eliminate such issues as fear of self ad-ministration with needles, and needle stick and cross contamination.

La présente invention concerne des systèmes et procédés de traitement de besoins médicaux non encore satisfaits dans le domaine des migraines et des affections associées comme la céphalée vasculaire de Horton. L'invention concerne des traitements qui agissent à la fois rapidement et sur le long terme, grâce au recours à des formes à libération prolongée et à des produits combinés. L'invention concerne encore des traitements applicables à de multiples symptômes de la migraine, en particulier les céphalées, les nausées et les vomissements. L'invention concerne des systèmes autonomes, portables, préremplis et simples à s'auto-administrer dès le début d'une crise de migraine. Ils comportent, de préférence, un dispositif d'injection sans aiguille et une forme pharmaceutique très visqueuse, afin d'éviter des problèmes tels qu'anxiété face à une auto-injection faisant appel à une aiguille, piqûres d'aiguille et contaminations croisées.

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