A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 47/12 (2006.01) A61K 47/48 (2006.01)
Patent
CA 2650056
The present invention addresses an ongoing need in the art to improve the stability of immunogenic compositions such as polysaccharide-protein conjugates and protein immunogens. The invention broadly relates to novel formulations which stabilize and inhibit precipitation of immunogenic compositions. More particularly, the invention described hereinafter, addresses a need in the art for formulations which stabilize and inhibit particulate formation (e.g., aggregation, precipitation) of immunogenic compositions which are processed, developed, formulated, manufactured and/or stored in container means such as fermentors, bioreactors, vials, flasks, bags, syringes, rubber stoppers, tubing and the like.
La présente invention vise à satisfaire un besoin permanent dans la technique d'améliorer la stabilité de compositions immunogènes telles que des conjugués polysaccharide/protéine et des immunogènes protéiniques. L'invention concerne au sens large de nouvelles formulations qui stabilisent et inhibent la précipitation de compositions immunogènes. Plus particulièrement, l'invention décrite ci-après vise à satisfaire un besoin de la technique pour des formulations qui stabilisent et inhibent une formation particulaire (par exemple une agrégation, une précipitation) de compositions immunogènes qui sont traitées, développées, formulées, fabriquées et/ou stockées dans des récipients tels que des fermenteurs, des bioréacteurs, des flacons, des ballons, des poches, des seringues, des bouchons en caoutchouc, des tubulures et similaires.
Chen Ying
Han Hanyoung
Jin Zhaowei
Khandke Lakshmi
Look Jee Loon
Torys Llp
Wyeth
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