Novel fully human anti-vap-1 monoclonal antibodies

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/13 (2006.01) A61K 39/395 (2006.01) C07K 16/28 (2006.01) C07K 16/40 (2006.01) C12N 9/06 (2006.01)

Patent

CA 2683079

Novel fully human anti-VAP-1 antibodies and fragments thereof are disclosed. Nucleic acids encoding anti-VAP-1 antibodies or fragments thereof, as well as expression vectors and host cells incorporating these nucleic acids for the recombinant expression of anti-VAP-1 antibodies are also given. Pharmaceutical compositions comprising said antibodies and therapeutic uses thereof are also disclosed.

L'invention porte sur de nouveaux anticorps anti-VAP-1 entièrement humains et sur des fragments de ceux-ci. L'invention porte également sur des acides nucléiques codant pour des anticorps anti-VAP-1 ou des fragments de ceux-ci, ainsi que sur des vecteurs d'expression et cellules hôtes incorporant ces acides nucléiques pour l'expression recombinante d'anticorps anti-VAP-1. L'invention porte également sur des compositions pharmaceutiques comprenant lesdits anticorps et leurs utilisations thérapeutiques.

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