Novel g protein coupled receptor protein, dna and its ligand

Details Novel g protein coupled receptor protein, dna and its ligand Novel g protein coupled receptor protein, dna and its ligand

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) A61P 15/06 (2006.01) A61P 35/00 (2006.01) C07K 14/705 (2006.01) C07K 16/28 (2006.01) C12P 21/08 (2006.01) C12Q 1/68 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2347294

G Protein-coupled receptor proteins originating in the vicinity of rat brain stem and human brain or salts thereof, or peptide fragments thereof or amides, esters or salts of the same; ligands thereto; a method/kit for screening compounds capable of altering the binding properties of the ligands to the G protein-coupled receptor proteins; the compounds or salts thereof obtained by the above screening; antibodies against the G protein-coupled receptor proteins, etc.

L'invention concerne des protéines réceptrices couplées aux protéines G tirées du voisinage du tronc cérébral du rat et du cerveau humain, ou leurs sels, leurs fragments peptidiques ou leurs amides, esters ou sels, leurs ligands, une méthode/un kit de criblage de composés capable de modifier les propriétés de liaison des ligands aux protéines réceptrices couplées aux protéines G, leurs composés ou sels obtenus par le criblage précité, des anticorps contre les protéines réceptrices couplées aux protéines G, etc.

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