Novel g-protein coupled receptors

Details Novel g-protein coupled receptors Novel g-protein coupled receptors

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) A61K 35/00 (2006.01) A61K 45/00 (2006.01) C07K 14/705 (2006.01) C07K 16/28 (2006.01) C12N 5/10 (2006.01) C12N 15/63 (2006.01) C12P 21/02 (2006.01) C12Q 1/68 (2006.01) G01N 33/566 (2006.01)

Patent

CA 2471465

The invention provides isolated nucleic acid and amino acid sequences of four novel G-protein coupled receptors that are amplified in breast cancer cells, antibodies to such receptors, methods of detecting such nucleic acids and receptors, and methods of screening for modulators of G-protein coupled receptors.

L'invention a trait à des séquences isolées nucléotidiques et d'acides aminés de quatre nouveaux récepteurs couplés aux protéines G qui sont amplifiés dans les cellules cancéreuses du sein, à des anticorps dirigés contre de tels récepteurs, à des méthodes de détection de tels acides nucléiques et récepteurs, et à des méthodes de criblage de modulateurs de récepteurs couplés aux protéines G.

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