Novel galectin sequences and compositions and methods...

A - Human Necessities – 61 – K

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A61K 38/00 (2006.01) A61K 39/00 (2006.01) C07H 21/04 (2006.01) C07K 16/28 (2006.01) C12N 1/20 (2006.01) C12N 15/74 (2006.01) C12P 21/06 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2505931

Isolated polynucleotides encoding novel galectin-8 variants polypeptides are provided. Also provided are methods and kits using same for diagnosing prognosing and treating rheumatoid arthritis (RA) and other joint / chronic inflammatory diseases.

L'invention concerne des polynucléotides isolés qui codent pour des polypeptides de nouvelles variantes génétiques de galectine 8. Elle concerne aussi des méthodes et des trousses utilisant ceux-ci pour diagnostiquer, pronostiquer et traiter la polyarthrite rhumatoïde et d'autres maladies inflammatoires chroniques ou articulaires.

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