A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/16 (2006.01)
Patent
CA 2591597
The invention concerns a novel galenic system with prolonged stability. Said system enables an active principle to be protected, in particular a drug, against degradation while passing through the stomach upon oral absorption. In particular, the invention concerns a galenic system, in the form of strictly hydrophobic solid lipid particles, not containing any water, surfactants, emulsifying agents, solvent traces, characterized in that it comprises at least one active principle, at least one hydrophobic wax and at least one agent neutralizing the embedded active principle.
La présente invention concerne un nouveau système galénique dont la stabilité est prolongée. Ledit système permet la protection d'un actif, particulièrement d'un médicament, contre sa dégradation lors du transit dans l'estomac lors d'une absorption par voie orale. Particulièrement, l'invention a pour objet un système galénique, sous forme de particules lipidiques solides, strictement hydrophobe, ne contenant strictement pas d'eau, ni de tensioactifs, ni d'agents émulsionnants, ni de traces de solvants, caractérisé en ce qu'il comprend au moins un principe actif, au moins une cire hydrophobe et au moins un agent neutralisant l'actif incorporé.
Ioualalen Karim
Raynal Rosanne
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Oralance Pharma
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