C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/12 (2006.01) A01K 67/027 (2006.01) A61K 38/17 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) C12N 5/10 (2006.01) G01N 33/566 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2309677
A nucleic acid molecule, designated Sel-1L (Sel-1 like; also previously known as Hip-1), which is widely expressed in adult mouse and human tissues with particularly high levels in the pancreas and in the floor plate of the neural tube. Sel-1L has also been localized within intracellular vesicles. The gene maps to 14q24.3-31 in close proximity to the insulin diabetes locus (IDDML). The nucleic acid molecules encodes a protein designated "SEL-1L Protein".
L'invention concerne une molécule d'acide nucléique, appelée Sel-IL (de type Sel-1, connue aussi sous le nom de Hip-1), qui est largement exprimée dans les souris adultes et les tissus humains avec des taux particulièrement élevés dans le pancréas et dans la partie plancher du tube neural. La Sel-IL peut aussi être localisée dans les vésicules intracellulaires. Le gène couvre 14q24.3-31 à proximité du locus du diabète insulino-dépendant (IDDML). La molécule d'acide nucléique code une protéine appelée "protéine SEL-IL".
Bernstein Alan
Donoviel Dorit
Mount Sinai Hospital
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
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