C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/85 (2006.01)
Patent
CA 2672981
The present invention relates to transgenic animals, as well as compositions and methods relating to the characterization of gene function. Specifically, the present invention provides transgenic mice comprising disruptions in PRO57290 genes. Such in vivo studies and characterizations may provide valuable identification and discovery of therapeutics and/or treatments useful in the prevention, amelioration or correction of diseases or dysfunctions associated with gene disruptions such as cardiovascular, endothelial or angiogenic disorders; immunological disorders; oncological disorders; bone metabolic abnormalities or disorders; or developmental abnormalities.
La présente invention concerne des animaux transgéniques, ainsi que des compositions et des procédés associés à la caractérisation de la fonction de gènes. La présente invention concerne notamment des souris transgéniques comprenant des disruptions dans les gènes PRO57290. De telles études in vivo et caractérisations peuvent permettre l'identification et la découverte d'agents thérapeutiques et/ou de traitements utiles pour la prévention, l'amélioration ou la correction de maladies ou de dysfonctionnements associés avec des disruptions géniques, par exemple des maladies cardiovasculaires, endothéliales ou angiogéniques ; des troubles immunologiques ; des troubles oncologiques ; des troubles ou des anomalies du métabolisme osseux ; ou des anormalités du développement.
Cunningham Jaime-Jo
Vogel Peter
Lexicon Pharmaceuticals Inc.
Smart & Biggar
LandOfFree
Novel gene disruptions, compositions and methods relating... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Novel gene disruptions, compositions and methods relating..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Novel gene disruptions, compositions and methods relating... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1988108