Novel gene encoding male-transplantation antigen

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/12 (2006.01) A61K 39/395 (2006.01) C07K 14/435 (2006.01) C07K 14/705 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2272987

Novel nucleotide sequences and corresponding polypeptide and peptide sequences are disclosed encoding a novel H-Y antigen or epitope thereof. Also disclosed are methods for treatment of transplantation-related diseases, wherein a novel nucleotide sequence, and corresponding polypeptide and peptide sequences encoding the novel H-Y antigen or epitope thereof are used as therapeutic agents to treat such diseases.

L'invention porte sur de nouvelles séquences nucléotidiques, ainsi que sur les séquences polypeptidiques et peptidiques correspondantes, codant un nouvel antigène H-Y ou son déterminant antigénique. Elle concerne également des méthodes thérapeutiques, s'agissant de maladies liées à une transplantation, utilisant comme agents thérapeutiques la nouvelle séquence nucléotidique ainsi que les séquences polypeptidiques et peptidiques correspondantes codant le nouvel antigène H-Y ou son déterminant antigénique.

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