Novel gene-up regulated in regenerating liver

Details Novel gene-up regulated in regenerating liver Novel gene-up regulated in regenerating liver

C - Chemistry, Metallurgy

12

N

C12N 15/15 (2006.01) A01K 67/027 (2006.01) A61K 31/70 (2006.01) A61K 35/407 (2006.01) A61K 38/57 (2006.01) A61K 39/395 (2006.01) A61K 48/00 (2006.01) C07K 14/475 (2006.01) C07K 14/81 (2006.01) C07K 16/38 (2006.01) C12N 5/08 (2006.01) C12Q 1/68 (2006.01) G01N 33/53 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2223707

The novel gene, Rasp-1, which is up-regulated in regenerating liver, is disclosed. The novel RASP-1 protein, which is encoded by the Rasp-1 gene, is also disclosed. In addition, antibodies against the Rasp-1 gene products are also disclosed. Furthermore, the use of Rasp-1 nucleic acid sequences, Rasp-1 gene products, and antibodies against Rasp-1 gene products in the treatment and diagnosis of liver disorders is also disclosed.

L'invention concerne un nouveau gène, Rasp-1, qui est régulé positivement dans un foie en cours de régénération, la nouvelle protéine RASP-1 codée par le gène Rasp-1 et des anticorps dirigés contre les produits du gène Rasp-1. En outre, l'invention concerne l'utilisation de séquences nucléotidiques de Rasp-1, des produits du gène Rasp-1 et d'anticorps dirigés contre les produits du gène Rasp-1, pour le traitement et le diagnostic d'affections du foie.

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