C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/38 (2006.01) A61K 31/56 (2006.01) A61K 31/70 (2006.01) A61K 39/395 (2006.01) C07H 21/00 (2006.01) C07K 16/44 (2006.01) C12N 15/11 (2006.01) C12N 15/85 (2006.01) C12Q 1/02 (2006.01) C12Q 1/70 (2006.01) A61K 48/00 (2006.01)
Patent
CA 2212379
The invention features an isolated herpersvirus glucocorticoid response element comprising a DNA sequence comprising two consensus hexanucleotide glucocorticoid receptor binding sequences having at least five nucleotides positioned therebetween. The invention further features compositions and methods for preventing herpesvirus replication and reactivation.
L'invention concerne un élément de réaction isolé de glucocorticoïde de virus de l'herpès comprenant une séquence d'ADN composée de deux séquences de consensus d'hexanucléotides de fixation du récepteur de glucocorticoïde, possédant au moins cinq nucléotides en position intermédiaire. L'invention concerne également des compositions et des procédés servant à empêcher la réplication et la réactivation du virus de l'herpès.
Hardwicke Mary Anne
Schaffer Priscilla A.
Dana Farber Cancer Institute
Gowling Lafleur Henderson Llp
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