C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/54 (2006.01) A61K 31/70 (2006.01) A61K 38/45 (2006.01) C07K 16/40 (2006.01) C12N 9/10 (2006.01) C12Q 1/48 (2006.01) G01N 33/573 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2212786
This invention relates to glutamine:fructose-6-phosphate amidotransferase, or its partial peptide or a salt thereof; a DNA coding for the protein; a recombinant vector; a transformant; a method for producing the protein; a pharmaceutical composition comprising the protein, its partial peptide or a salt thereof; and an antibody against the protein or its partial peptide. The protein, its partial peptide or a salt thereof, and the DNA are useful for a prophylactic or therapeutic agent for hypoglycemia. The antibody can be used in the assay of the protein, its partial peptide or a salt thereof. The protein, its partial peptide or a salt thereof is useful as a reagent for the screening for candidate medical compounds.
L'invention porte sur la glutamine:fructose-6-phosphate-amidotransférase, son peptide partiel ou son sel; ADN codant la protéine; vecteur recombinant; transformant; méthode pour produire la protéine; composition pharmaceutique renfermant la protéine, son peptide partiel ou son sel; anticorps actif contre la protéine ou son peptide partiel. La protéine, son peptide partiel ou son sel, ainsi que l'ADN sont utiles pour un agent de prévention ou de traitement de l'hypoglycémie. L'anticorps peut être utilisé pour le dosage de la protéine, de son peptide partiel ou de son sel. La protéine, son peptide partiel ou son sel sont utiles comme réactifs pour le dépistage de composés médicaux potentiels.
Hikichi Yukiko
Nishi Kazunori
Shintani Yasushi
Fetherstonhaugh & Co.
Takeda Chemical Industries Ltd.
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