Novel glycolipid and medicine for autoimmune disease...

C - Chemistry – Metallurgy – 07 – H

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C07H 15/04 (2006.01) A61K 31/7028 (2006.01) A61P 37/02 (2006.01) A61P 37/06 (2006.01) A61P 43/00 (2006.01) C07H 15/10 (2006.01)

Patent

CA 2459482

The present invention provides a glycolipid represented by the formula below (I). (see formula I) In the formula, R1 is an aldopyranose group, R2 is a hydrogen atom or a hydroxyl group, R3 is -CH2-, -CH(OH)-CH2- or -CH=CH-, R4 is a hydrogen atom or CH3, x is 0-35, y and z represent integers satisfying y + z = 0-3. The glycolipid of the invention is useful in treating autoimmune diseases.

La présente invention concerne un glycolipide utile pour les traitements de maladies auto-immunes ; et un remède contre les maladies auto-immunes qui contient ledit glycolipide en tant qu'ingrédient actif. Ledit glycolipide est représenté par la formule suivante (I), où R?1¿ représente un résidu aldopyranose ; R?2¿ représente un groupe hydrogène ou hydroxy ; R?3¿ représente -CH¿2?-, -CH(OH)-CH¿2?, ou -CH=CH- ; R?4¿ représente un groupe hydrogène ou CH¿3? ; x représente de 0 à 35 ; et y et z représentent chacun un entier satisfaisant la relation 0 <= y+z <= 3.

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