Novel helicobacter pylori-binding substances and use thereof

Details Novel helicobacter pylori-binding substances and use thereof Novel helicobacter pylori-binding substances and use thereof

C - Chemistry, Metallurgy

07

H

C07H 15/10 (2006.01) A23L 1/30 (2006.01) A61K 31/702 (2006.01) A61K 31/715 (2006.01) A61K 47/48 (2006.01) A61P 1/04 (2006.01) A61P 31/04 (2006.01) C07H 5/06 (2006.01) C07H 15/00 (2006.01) C07H 15/04 (2006.01) C08B 37/00 (2006.01) G01N 33/53 (2006.01) G01N 33/569 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2392766

Helicobacter pylori-binding substances comprising Gal.beta.3GlcNAc or Gal.beta.3GalNAc are described, as well as use thereof in pharmaceutical compositions and food-stuff, and methods for treatment of conditions due to the presence of Helicobacter pylori. Also use of said substance for the identification of bacterial adhesions, for the production of a vaccine against Helicobacter pylori, for diagnosis of Helicobacter pylori infections, for typing of Helicobacter pylori, for identification of Helicobacter pylori binding substances and for inhibition of the binding of Helicobacter pylori is described.

L'invention concerne des substances de liaison d'Helicobacter pylori comprenant Gal.beta.3GlcNAc ou Gal.beta.3GalNAc, leur utilisation dans les compositions pharmaceutiques et les aliments et les traitements des pathologies liées à la présence d'Helicobacter pylori. Cette substance trouve en outre une application dans l'identification d'adhésions bactériennes, la production d'un vaccin contre l'Helicobacter pylori, le diagnostic des infections dues à l'Helicobacter pylori, le typage de l'Helicobacter pylori, l'identification de substances de liaison avec l'Helicobacter pylori et l'inhibition de la liaison de l'Helicobacter pylori.

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