Novel heparin binding peptides

Details Novel heparin binding peptides Novel heparin binding peptides

C - Chemistry, Metallurgy

07

K

C07K 7/08 (2006.01) A61K 38/10 (2006.01) A61K 38/16 (2006.01) A61K 38/28 (2006.01) C07K 14/00 (2006.01) C07K 17/10 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2285151

The present invention provides heparin antagonist peptides. The heparin- binding peptides of the present invention specifically neutralize heparin's conventional anticoagulant properties without causing deleterious hemodynamic side-effects or exacerbation of the proliferative vascular response to injury. More specifically, the heparin-binding compounds of the present invention are short- duration drugs to be used in elective or emergency situations which can safely and specifically neutralize heparin's conventional anticoagulant properties without causing deleterious hemodynamic side-effects or exacerbation of the proliferative vascular response to injury.

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