C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/12 (2006.01) A61K 31/70 (2006.01) A61K 38/18 (2006.01) A61K 39/395 (2006.01) C07K 14/50 (2006.01) C12Q 1/68 (2006.01) G01N 33/53 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2385127
The present invention provides HDGFX, a novel isolated polypeptide, as well as a polynucleotide encoding HDGFX and antibodies that immunospecifically bind to HDGFX or any derivative, variant, mutant, or fragment of the HDGFX polypeptide, polynucleotide or antibody. The invention additionally provides methods in which the HDGFX polypeptide, polynucleotide and antibody are used in detection and treatment of a broad range of pathological states, as well as to other uses.
L'invention concerne un facteur de croissance dérivé de l'hépatome (HDGFX), un nouveau polypeptide isolé, ainsi qu'un polynucléotide codant pour HDGFX, et des anticorps qui se lient de manière immunospécifique à HDGFX ou à tout dérivé, variant, mutant, ou fragment du polypeptide, du polynucléotide ou de l'anticorps de HDGFX. L'invention concerne également des méthodes utilisant lesdits polypeptide, polynucléotide ou anticorps de HDGFX pour détecter et traiter une large plage d'états pathologiques, ainsi que d'autres utilisations.
Boldog Ferenc L.
Burgess Catherine
Larochelle William
Minskoff Stacey
Shimkets Richard A.
Curagen Corporation
Ridout & Maybee Llp
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