Novel heteroaryl carboxamide derivatives

Details Novel heteroaryl carboxamide derivatives Novel heteroaryl carboxamide derivatives

C - Chemistry, Metallurgy

07

D

C07D 401/14 (2006.01) A61K 31/437 (2006.01) A61K 31/4468 (2006.01) A61P 1/00 (2006.01) A61P 9/00 (2006.01) A61P 19/02 (2006.01) A61P 25/00 (2006.01) C07D 471/04 (2006.01)

Patent

CA 2725657

The invention is concerned with novel heteroaryl carboxamide derivatives of Formula (I), wherein (II), m, X, Y, R1, R2, R3 and R4 are as defined in the description and in the claims, as well as physiologically acceptable salts thereof. These compounds are antagonists of CCR-2 receptor, CCR-5 receptor and/or CCR-3 receptor and can be used as medicaments.

La présente invention concerne de nouveaux dérivés de carboxamide dhétéroaryle représentés par la formule (I), dans laquelle (II), m, X, Y, R1, R2, R3 et R4 sont tels que définis dans la description et dans les revendications, ainsi que leurs sels physiologiquement acceptables. Ces composés sont des antagonistes des récepteurs CCR-2, CCR-5 et/ou CCR-3 et peuvent être utilisés en tant que médicaments.

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