Novel heterocycles

C - Chemistry – Metallurgy – 07 – D

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C07D 239/26 (2006.01) A61K 31/505 (2006.01) C07D 401/04 (2006.01) C07D 403/04 (2006.01)

Patent

CA 2637631

The present invention relates to novel heterocyclic compounds of the general formula (I), their derivatives, analogs, tautomeric forms, stereoisomers, polymorphs, hydrates, solvates, pharmaceutically acceptable salts and compositions, metabolites and prodrugs thereof. The present invention more particularly provides novel hetereocycles of the general formula (I). Also included is a method of treatment of immunological diseases, inflammation, pain disorder, rheumatoid arthritis; osteoporosis; multiple myeloma; uveititis; acute and chronic myelogenous leukemia; ischemic heart disease; atherosclerosis; cancer; ischemic-induced cell damage; pancreatic beta cell destruction; osteoarthritis; rheumatoid spondylitis; gouty arthritis; inflammatory bowel disease; adult respiratory distress syndrome (ARDS); psoriasis; Crohn's disease; allergic rhinitis; ulcerative colitis; anaphylaxis; contact dermatitis; muscle degeneration; cachexia; asthma; bone resorption diseases; ischemia reperfusion injury; brain trauma; multiple sclerosis; sepsis; septic shock; toxic shock syndrome; fever, and myalgias due to infection in a mammal comprising administering an effective amount of a compound of formula (I) as described above.

L'invention concerne de nouveaux composés hétérocycliques de formule générale (I), leurs dérivés, analogues, formes tautomères, stéréoisomères, polymorphes, hydrates, solvates, sels et compositions pharmaceutiquement acceptables, métabolites et promédicaments de ces composés. L'invention concerne plus particulièrement de nouveaux hétérocycles de formule générale (I). L'invention concerne en outre un procédé de traitement de maladies immunologiques, inflammation, troubles dus à la douleur, polyarthrite rhumatoïde; ostéoporose, myélome multiple; uvéite; leucémie myélogène aiguë ou chronique; maladies cardiaques ischémiques; athérosclérose; cancer; dégâts cellulaires ischémiques; destruction cellulaire; destruction cellules bêta pancréatiques; ostéoarthrite; spondylitis rhumatoïde; arthrite goutteuse; inflammation de l'intestin; syndrome de détresse respiratoire aigu (ARDS); psoriasis, maladie de Crohn; rhinite allergique; rectocolite hémorragique; anaphhylaxie; desmatite par contact; dégénérescence musculaire; cachéxie; asthme; maladies de résorption osseuse; lésion ischémique reperfusion; traumatisme cranien; sclérose en plaques; sepsis; choc septique; syndrome choc toxique; fièvre; myalgie due à une infection chez un mammifère, ledit procédé comprenant l'administration d'une quantité efficace d'un composé de formule (I) tel que précédemment décrit.

LandOfFree

Say what you really think

Search LandOfFree.com for Canadian inventors and patents. Rate them and share your experience with other people.

Rating

Novel heterocycles does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Novel heterocycles, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Novel heterocycles will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFCA-PAI-O-1517372

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.